Multidrug-resistant Neisseria gonorrhoeae

Multidrug-resistant Neisseria gonorrhoeae.

Multidrug-resistant strains of Neisseria gonorrhoeae in Greece.

Eighty-seven out of 575 gonococci isolated in Greece from 1991 to 1998 belonged to serovar Bropyst and exhibited resistance to penicillin, tetracycline, erythromycin, and chloramphenicol. Conventional and molecular typing showed three clusters, A, B, and C, that were associated with networks of high- frequency transmitters (cluster A with homosexuals and clusters B and C with refugees from East...

Ciprofloxacin resistant Neisseria gonorrhoeae.

Ceftriaxone-Resistant Neisseria gonorrhoeae, Japan

To the Editor: Spread of multi-drug-resistant Neisseria gonorrhoeae is a major public health concern. Effective antimicrobial therapy is a key element in gonorrhea control. However , N. gonorrhoeae has developed resistance to multiple classes of anti-microbial drugs, including β-lactams, tetracyclines, and fl uoroquinolones (1–3). Even an extended-spectrum oral cephalosporin-resistant, cefi xim...

Optimizing Treatment of Antimicrobial-resistant Neisseria gonorrhoeae

The increasing prevalence of ciprofloxacin-resistant Neisseria gonorrhoeae has required replacing inexpensive oral ciprofloxacin treatment with more expensive injectable ceftriaxone. Further, monitoring antimicrobial resistance requires culture testing, but nonculture gonorrhea tests are rapidly replacing culture. Since the strategies were similar in effectiveness (> 99%), we evaluated, from th...